General information Fumaric acid esters are used to treat a variety of skin disorders, including psoriasis [ ], cutaneous sarcoidosis [ ], necrobiosis lipoidica diabeticorum [ ], and disseminated granuloma annulare [ ]. Dimethylfumarate has been used in the treatment…
General information Attention has been drawn to the use of fructose-based and sorbitol-based solutions for parenteral administration in Germany and German-speaking countries, where they are available for routine fluid replacement and intravenous feeding, and are widely prescribed, even after minor…
General information Preparations from the gum resin of Boswellia serrata have been used as traditional remedies in Ayurvedic medicine in India for inflammatory diseases [ ]. The gum contains substances that have anti-inflammatory properties; they are pentacyclic triterpenes related to…
See also Opioid receptor agonists General information Frakefamide is a peripherally acting opioid MOR (μ or OP 3 ) receptor agonist. It has restricted penetration of the blood–brain barrier into the central nervous system and has selective MOR receptor agonist…
General information The fragrance mix, introduced in 1977 by Larsen [ ], is used to detect sensitivity to fragrances in, for example, cosmetics and household products [ ]. The mix contains eight widely used fragrance compounds. Additional indicators of fragrance…
General information Fosmidomycin is an antimicrobial drug that acts by inhibiting 1-deoxy- d -xylulose 5-phosphate reductoisomerase, a key enzyme of the non-mevalonate pathway of isoprenoid biosynthesis. It inhibits the synthesis of isoprenoids by Plasmodium falciparum and suppresses the growth of…
See also Angiotensin-converting enzyme inhibitors General information Fosinopril is a phosphorus-containing ester prodrug of the ACE inhibitor fosinoprilat. Its clinical pharmacology, clinical use, and safety profile have been reviewed [ ]. Organs and systems You’re Reading a Preview Become a…
General information Fosfomycin is a broad-spectrum antibiotic used to treat uncomplicated lower urinary tract infections. It penetrates interstitial space fluids of soft tissues well and reaches concentrations sufficient to substantially inhibit the growth of relevant bacteria at the target site…
General information Foscarnet (trisodium phosphonoformate hexahydrate) is a pyrophosphate analogue that interacts with the enzymatic action of polymerases and inhibits the cleavage of pyrophosphate from the nucleoside triphosphate. Because of this mechanism, the antiviral activity of the drug is broad.…
See also Beta 2 -adrenoceptor agonists General information Formoterol is a long-acting selective β 2 -adrenoceptor agonist that is more potent than salmeterol [ ] and has a similar duration of action (12 hours) but a rapid onset of effect…