General information Activated charcoal is a standard therapy for gut decontamination after self-poisoning. It has two uses. If given within an hour or two after acute self-poisoning it can adsorb the drug and prevent it from being absorbed; in this…
General information Local biocompatibility Although polymerized polymethylmethacrylate is a biocompatible material, it is not biocompatible during the brief time it takes to set, during which it releases 130 calories/gram and can cause a rise in temperature up to 120 °C.…
See also Antihistamines General information Acrivastine is a second-generation antihistamine that has not been the subject of recent studies; earlier work was insufficient to substantiate statements that it was non-sedating. You’re Reading a Preview Become a Clinical Tree membership for…
See also Disinfectants and antiseptics General information Acrisorcin (aminoacridine 4-hexylresorcinolate) has been used in the treatment of tinea versicolor [ ] and for induction of abortion in mid-trimester pregnancies. You’re Reading a Preview Become a Clinical Tree membership for Full…
See also Herbal medicines General information Acorus calamus was originally classified as a member of the arum family (Araceae), but is now designated as belonging to its own family, the Acoraceae, of which it is the only member. You’re Reading…
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General information Acipimox (S-methylpyrazine-2-carboxylic acid 4-oxide) is structurally related to nicotinic acid. There were flushing and gastrointestinal disturbances in 7137 patients, of whom 15% stopped taking the drug because of adverse effects; there were no adverse effects on blood glucose…
General information Aciclovir is an acyclic purine nucleoside. Its antiviral activity depends upon intracellular phosphorylation to its triphosphate derivative. Because of its higher affinity for viral thymidine kinase, aciclovir is phosphorylated at a much higher rate by the viral enzyme.…
See also Benorilate ; Diflunisal ; Lysine acetylsalicylate ; Salicylates, topical ; Salsalate General information Over a century after its introduction, acetylsalicylic acid (aspirin) is by far the most commonly used analgesic, sharing its leading position with the relative newcomer…
General information Acetylcysteine (N-acetylcysteine) is used as a mucolytic and to treat paracetamol overdose. Acetylcysteine splits disulfide bonds in mucoproteins and thus lowers mucus viscosity, resulting in a larger volume of sputum. It is normally administered by inhalation as a…