Acknowledgments Dr. Sempoux extends very special thanks to Professor Darius Moradpour and Dr. Sabine Schmidt-Kobbe (CHUV, Lausanne, Switzerland) for their critical clinical advice in formulating this chapter. The term cirrhosis is derived from the Greek word “kirrhos” meaning “yellow” or…
Abbreviations CPA collagen proportionate area ECM extracellular matrix HRC hepatic repair complex HSC hepatic stellate cell MF myofibroblast MMP matrix metalloproteinase SMA smooth muscle actin TIMP tissue inhibitor of metalloproteinase Regression of fibrosis is no longer a mythical concept. First…
Abbreviations AFP alpha fetoprotein CC cholangiocarcinoma CHC combined hepatocellular-cholangiocarcinoma CEA carcinoembryonic antigen EpCAM epithelial cell adhesion molecule HCC hepatocellular carcinoma K a keratin a Although the prefix CK is widely used in surgical pathology to designate human cytokeratins, consensus nomenclature…
Abbreviations AIH autoimmune hepatitis AMR antibody-mediated rejection BMI body mass index cAMR chronic antibody-mediated rejection CMV cytomegalovirus DAA direct-acting antivirus DCD donation after (cardiac) circulatory death DSA donor-specific EBV Epstein-Barr virus FCH fibrosing cholestatic hepatitis HBcAg hepatitis B core antigen…
Abbreviations AIH autoimmune hepatitis ALD alcoholic liver disease ALF acute liver failure AST aspartate aminotransferase CDC Center of Disease Control and Prevention CI calcineurin inhibitor CKD chronic kidney disease CMV cytomegalovirus Cr creatinine DAA direct-acting antiviral DCD donation after cardiac…
Abbreviations CK cytokeratin a a Although the prefix CK is widely used in surgical pathology to designate human cytokeratins, consensus nomenclature recommends the replacement of “cytokeratin” with “keratin” and the prefix “CK” with “K.” (Schweizer J, Bowden PE, Coulombe PA,…
Abbreviations AFP alpha fetoprotein ATRT atypical teratoid/rhabdoid tumor COG Children’s Oncology Group CT computed tomography E-HB epithelial hepatoblastoma EMT epithelial-mesenchymal transitional EpCAM epithelial cell adhesion molecule FGFR fibroblast growth factor receptor FLC fibrolamellar carcinoma FNH focal nodular hyperplasia GPOH German…
Abbreviations CA cancer antigen CC cholangiocarcinoma CEA carcinoembryonic antigen CT computed tomography HCC hepatocellular carcinoma HCC-CC hepatocellular-cholangiocarcinoma ICC intrahepatic cholangiocarcinoma IPMN intraductal papillary mucinous neoplasm IPNB intraductal papillary neoplasm of bile duct K a keratin a Although the prefix CK…
Abbreviations AFB1 aflatoxin B1 AFP alpha fetoprotein CEA carcinoembryonic antigen DN dysplastic nodule FL-HCC fibrolamellar hepatocellular carcinoma GPC3 glypican 3 HBV hepatitis B virus HCA hepatocellular adenoma HCC hepatocellular carcinoma HCV hepatitis C virus HepPar-1 hepatocyte paraffin-1 K keratin a…
Abbreviations ANGPT angiopoietin b-HCA β-catenin–activated HCA b-IHCA β-catenin–activated inflammatory HCA CEUS contrast-enhanced ultrasound CRP C-reactive protein FNH focal nodular hyperplasia GS glutamine synthetase H&E hematoxylin and eosin HBP hepatobiliary phase HCA hepatocellular adenoma HCC hepatocellular carcinoma H-HCA HNF1α-inactivated HCA HNF1α…