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Pediatric Globe Lesions
A 7-year-old boy with bilateral leukocoria and nystagmus. Ax, axial; CT, computed tomography.
A 2-year-old boy with right-sided leukocoria. Ax, axial; CT, computed tomography.
DESCRIPTION OF FINDINGS
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Case A: An axial CT image through the orbits shows small globes bilaterally with abnormal retrolental soft tissue density. Axial T2-weighted MRI more clearly reveals a triangular configuration of this T2-hypointense intraocular soft tissue. T1-weighted precontrast and postcontrast images show abnormally hyperintense vitreous with mild enhancement within the left retrolental soft tissue.
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Case B: Axial CT image demonstrates a calcified lentiform mass in the normal-sized right globe. Axial T2-weighted MRI shows corresponding T2 hypointensity of the lesion relative to the surrounding vitreous. An axial T1-weighted postcontrast image demonstrates mild enhancement.
Diagnosis
Case A
Persistent hyperplastic primary vitreous (PHPV)
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