D efinition — Unavoidable loss of viability in the first 12 weeks. Clinical Features Epidemiology Approximately one third of clinically known pregnancies terminate in the first 12 weeks. Forty to fifty percent have a chromosomal anomaly. Twenty percent have trisomy…
D efinition — A collection of extravillous trophoblasts within hyalinized stroma, indicative of a previous pregnancy. Clinical Features Epidemiology Implantation site nodules are common and typically have the same immunophenotype as epithelioid trophoblasts seen in the membranes, maternal surface, and…
PITFALL D efinition — The area adjacent to the gestational sac where intermediate trophoblasts and fibrinoid can be found permeating the decidua. Clinical Features Epidemiology Normal structure. You’re Reading a Preview Become a Clinical Tree membership for Full access and…
D efinition — The membranous sac that envelops the developing embryo. Clinical Features Epidemiology The gestational sac can be identified in the majority of samples from previable pregnancies. The gestational sac confirms an intrauterine pregnancy, even in cases in which…
D efinition — Malignancy comprised of mesothelial cells. Clinical Features Epidemiology Malignant mesothelioma is an uncommon neoplasm that most often is found involving the pleura. Cases have been described within the abdomen; however, the majority of these cases have been…
D efinition — A benign, reactive condition consisting of hyperplastic mesothelial cells seen in association with acute and chronic irritation of the peritoneal surface. Clinical Features Epidemiology Papillary mesothelial hyperplasia is often found in cases of pelvic inflammatory disease, tubo-ovarian…
D efinition — A well-differentiated tumor of mesothelial cells. Clinical Features Epidemiology An uncommon neoplasm occurring in women between 20 and 50 years of age. Some but not all have evidence of asbestos exposure. You’re Reading a Preview Become a…
D efinition — A rare benign disease consisting of multiloculated mesothelial-lined cysts in the peritoneum. Also termed “multiloculated peritoneal cyst.” Clinical Features Epidemiology Rare. Reproductive-age women. History of a prior abdominal procedure or surgery is often noted. Controversy as to…
D efinition — A rare, predominantly intraabdominal tumor associated with a specific chromosomal translocation (t11;22)(p13:q12) that produces a fusion transcript EWS Clinical Features Epidemiology Extremely rare, particularly in women. Typically seen in children and young adults. Specific cell of origin…
D efinition — A rare, poorly differentiated embryonal neuroectodermal tumor sometimes associated with a teratoma that mimics the central type of primitive neuroectodermal tumor (PNET). Clinical Features Epidemiology Extremely rare in the ovary. Belongs in the Ewing's family of tumors…