D efinition — A parasitic infection often contracted by handling cat litter, which can result in significant fetal morbidity if primary maternal infection occurs in the first trimester. Clinical Features Epidemiology Affects approximately 3500 newborns each year in the United…
D efinition — Placental implantation within the lower uterine segment, overlying the cervical os. Clinical Features Epidemiology Placenta previa is a common finding in early pregnancy. The majority of cases spontaneously resolve during gestation. Less than 1% of cases persist…
D efinition — Abnormal adherence of the placenta to the uterine wall. Clinical Features Epidemiology Placenta creta occurs in 1 in 2500 pregnancies. Historically all subtypes of placenta cretas were rare. More than 80% of cases occur in patients with…
D efinition — A primary white blood cell malignancy arising in the fetus. Clinical Features Epidemiology Fetal leukemia is exceedingly rare and has an incidence of approximately four to five per million live births. Fetal leukemia is the leading cause…
D efinition — Fetal infection by the single-stranded DNA parvovirus B-19. Clinical Features Epidemiology Parvovirus infection is a common occurrence in adult life. Congenital parvovirus occurs when a woman who has not been exposed to parvovirus contracts the infection for…
D efinition — A localized form of abruption due to acute spiral arterial bleed into the basal parenchyma associated with maternal hypertension. Clinical Features Epidemiology Most commonly associated with maternal hypertension and preeclampsia. You’re Reading a Preview Become a Clinical…
D efinition — Early separation of the placental disk from the underlying maternal surface. Clinical Features Epidemiology Placental abruption is a relatively common event, with an overall incidence of 1%. Numerous predisposing factors are thought to lead to abruption but…
D efinition — Metabolic deficits within the fetus that lead to the accumulation of a metabolite, typically visible in the placental villi. Clinical Features Epidemiology Lysosomal storage disorders and their placental presentations are rare events. The vast majority of cases…
D efinition — Infection resulting from the spirochete Treponema pallidum . Clinical Features Epidemiology The frequency of congenital syphilis in developed countries is much lower; however, a recent rise in the incidence has been noted. It is rarely encountered in…
D efinition — Infiltration of the intervillous space by a monomorphic population of histiocytes. Clinical Features Epidemiology Uncommon. Histiocytic intervillositis is associated with spontaneous abortion and recurrent pregnancy loss. Rare cases of maternal malaria or recurrent sepsis have been documented.…