D efinition — A subset of extravillous trophoblastic tumor that is thought to arise from an extravillous (transitional) trophoblast that forms a transition from villous cytotrophoblast to mature extravillous trophoblast. These cells are found in the chorionic membrane, maternal surface…
D efinition — An abnormal early implantation site (IS) that can be identified in the setting of a molar pregnancy. Clinical Features Epidemiology Atypical molar ISs may be seen in the setting of any molar pregnancy. They are much more…
PITFALL D efinition —A malignancy that arises from the early implantation site extravillous trophoblasts. Clinical Features Epidemiology Placental site trophoblastic tumors (PSTT) are rare and were only recognized as a malignancy in 1981. PSTT are most commonly seen following a…
PITFALL D efinition — Choriocarcinoma occurring concurrently with a normal pregnancy. Clinical Features Epidemiology Intraplacental choriocarcinoma is exceedingly rare. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…
D efinition — A trophoblastic malignancy composed of syncytiotrophoblasts and cytotrophoblasts, intermediate trophoblasts of both. Clinical Features Epidemiology At least half of choriocarcinomas follow a molar pregnancy, but only 2% to 3% of complete moles are followed by a diagnosis…
PITFALL D efinition — An abnormally large placenta characterized by striking, cystically dilated stem villi, stromal overgrowth, and hypervascularity. Clinical Features Epidemiology Rare; case reports only. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…
D efinition — Gestational trophoblastic disease in which the conceptus contains a triploid (3n) amount of genetic material (typically 1n maternal and 2n paternal). Clinical Features Epidemiology Partial moles are 10 times more common than complete moles. The risk factors…
D efinition —A complete mole that invades into the underlying myometrium. Clinical Features Epidemiology Is defined as an uncommon sequel to complete mole, occurring in less than 5% of complete moles. Increased incidence has been noted in women of Asian…
PITFALL D efinition — An abnormal gestation in which all of the genetic material is paternally derived. Clinical Features Epidemiology Molar pregnancies have a biphasic age distribution, with increased incidence at the reproductive extremes: before age 20 and after age…
D efinition — Implantation of the embryo that occurs outside the uterine cavity or in an abnormal location within the uterus. Clinical Features Epidemiology Ectopic pregnancies account for around 2% of all documented pregnancies in the United States. Ectopic pregnancy…