Tag Michelle S. Hirsch MD PhD

Yolk Sac Tumor

D efinition —A malignant germ cell tumor with endodermal sinus or vitelline differentiation. Clinical Features Epidemiology The majority of patients are in their teens or twenties, although cases commonly occur in the first and fourth decades of life as well.…

Dysgerminoma

D efinition — A malignant, primitive germ cell tumor of the ovary that is the counterpart to testicular seminoma. Clinical Features Epidemiology Rare; represents only 1% of all ovarian germ cell tumors but is the most common malignant germ cell…

Metastatic Carcinoid

D efinition — Metastatic carcinoid, usually from the gastrointestinal tract. Clinical Features Epidemiology The majority of metastatic carcinoids are of distal ileal origin. Have a wide age range, but most will be postmenopausal. You’re Reading a Preview Become a Clinical…

Strumal Carcinoid

D efinition — A monodermal teratoma composed of both struma (thyroid) and a trabecular carcinoid. Clinical Features Epidemiology Strumal carcinoids are rare tumors with bidirectional differentiation, resulting in both thyroid and neuroendocrine differentiation. Seen over a wide age range, from…

Malignant Struma

D efinition — Malignant teratomatous thyroid tissue (carcinoma). Clinical Features Epidemiology Association with mature cystic teratomas and struma ovarii. Mean age is approximately 43 years. Approximately 5% of struma are malignant, at least focally. Some estimates are higher and this…

Struma Ovarii

D efinition — A teratoma composed principally of thyroid tissue. Clinical Features Epidemiology Struma ovarii is a monodermal ovarian teratoma predominantly composed of thyroid tissue. Seen most commonly in the fifth decade of life. Virtually always unilateral. Contralateral cystic teratoma…

Pseudomyxoma Peritonei

D efinition — A clinical term for increased mucin present within the abdominal cavity, typically associated with a low-grade mucinous tumor of the appendix or gastrointestinal tract. Clinical Features Epidemiology Pseudomyxoma is frequently associated with appendiceal neoplasms; however, occasional cases…