The small intestinal bacterial overgrowth (SIBO) syndrome may be caused by a disturbance in gastrointestinal (GI) motility, by an alteration in the anatomy of the intestine, or less likely, by a loss of gastric acid secretion. The disturbance usually causes…
Whipple disease is a systemic, infectious disease that primarily affects the small intestine and its lymphatic drainage, although it also has many extraintestinal manifestations, comparable to classic celiac disease ( Fig. 66.1 ). George Whipple first described the clinical syndrome…
Any disease that affects nutrient digestion or small bowel function or that compromises bowel circulation or motility may result in a malabsorption syndrome, which includes systemic vascular, infectious, and neoplastic diseases ( Fig. 65.1 ). This chapter and others in…
Since the time of Hippocrates, the term diarrhea has been used to designate abnormally frequent passage of loose stools. However, it is a subjective symptom. Patients describe any increased frequency or fluidity to mean diarrhea. It is generally accepted that…
Lactose intolerance occurs when there is a deficiency of lactase in the brush border of the small intestine. When a person with lactase deficiency ingests lactose, the poorly digested lactose is fermented in the small and large intestines, resulting in…
The rapid development of imaging and histopathologic techniques, in conjunction with an altered pattern of disease and treatments late in the 20th century, has changed the “standard” of testing for small bowel function and anatomy. Testing has now become a…
Irritable bowel syndrome (IBS) is one of a group of functional gastrointestinal (GI) disorders characterized by abdominal discomfort or pain and frequently associated with a change in bowel movements ( Fig. 61.1 ). Worldwide, IBS is the most frequent symptom…
Chronic intestinal pseudo-obstruction (CIPO) is a clinical syndrome that mimics the signs and symptoms of intestinal obstruction ( Fig. 60.1 ). In patients with CIPO, no mechanical obstructive lesion is found on evaluation. CIPO is now thought to be a…
Intestinal obstruction occurs when the onward passage of intestinal contents is limited by mechanical abnormalities or a functional disturbance ( Fig. 59.1 ). Peristaltic activity may be abolished by reflexes originating from diseased structures within, or remote from, the abdominal…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here