Suppurative Adenitis


KEY FACTS

Terminology

  • Pus formation within nodes from bacterial infection

  • Synonyms: Adenitis, lymphadenitis, intranodal abscess

Imaging

  • Enlarged node(s) with internal fluid & surrounding inflammation (cellulitis)

    • Most often jugulodigastric, submandibular, or retropharyngeal

  • Loss of normal nodal architecture & internal vascularity/enhancement

  • Conglomeration of necrotic nodes progressing to abscess shows marked heterogeneity of irregular collection

    • Well-defined enhancing/hyperemic wall

    • Complex hypoechoic/nonenhancing center

  • US useful to confirm true liquefaction with drainable pus

    • Swirling internal debris upon compression

  • CECT best defines deep extent & complications

    • Lemierre syndrome (venous thrombophlebitis), internal carotid artery spasm or pseudoaneurysm, airway compression, mediastinal extension

Top Differential Diagnoses

  • Nontuberculous Mycobacterium adenopathy, tuberculous adenopathy, 2nd branchial cleft anomaly, rhabdomyosarcoma, lymphoma, lymphatic malformation

Pathology

  • Staphylococcus & Streptococcus most frequent organisms

Clinical Issues

  • Painful neck mass, fever, poor oral intake; symptoms referable to primary infection

  • Treatment: Antibiotics

    • Incision & drainage for large suppurative nodes, abscesses, or poor response to antibiotics

Transverse (left) & longitudinal (right) color Doppler & grayscale US images of an infant with suppurative adenopathy show an enlarged, heterogeneous conglomeration of cervical nodes
with internal debris
, posterior acoustic enhancement
, & peripheral hyperemia
.

Transverse color Doppler US in a 6 year old with fever & a tender neck mass shows an irregular hypoechoic abscess
with posterior acoustic enhancement
, internal echoes, & no internal vascularity.

Coronal CECT in a 6 year old with fever & a fluctuant neck mass shows an irregular, rim-enhancing abscess
with overlying myositis/cellulitis
& an adjacent nonsuppurative lymph node
.

More inferior image from an axial CECT in the same child shows a round focus of nonenhancement representing segmental clot
in the right internal jugular vein, consistent with Lemierre syndrome. Note the right-greater-than-left nonsuppurative nodes
as well as the overlying myositis/cellulitis
.

TERMINOLOGY

Definitions

  • Pus formation within nodes from bacterial infection

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