Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Selective Estrogen Receptor Modulators
Uses
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Critical components in treatment algorithm for invasive and/or in situ breast cancer, breast cancer chemoprevention in high-risk pts, and postmenopausal osteoporosis (raloxifene only)
Perioperative Risks
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VTE, particularly if the pt has a history of recent chemotherapy, prior irradiation, or long-term SERM use
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Microvascular complications following free-flap breast reconstruction surgery
Worry About
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Periop SERM management
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Endometrial cancer (tamoxifen only)
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Unpleasant side effect profile affecting pt quality of life and medication adherence
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