See also Beta-adrenoceptor antagonists

General information

Propranolol is a lipophilic, non-selective, pure antagonist at beta-adrenoceptors, with membrane-stabilizing action.

Organs and systems

Cardiovascular

An unusual dysrhythmia has been attributed to propranolol: alternating sinus rhythm with intermittent sinoatrial block. The authors suggested that this was accounted for by the existence of sinoatrial conduction via two pathways, the first with 2:1 block and the second with a slightly longer conduction time and intermittent 2:1 block [ ].

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