Picibanil

General information

Picibanil (OK 432) is derived from Streptococcus pyogenes and has been used as a sclerosant in the treatment of cancers [ , ], lymphangiomas [ , ], benign neck cysts [ ], and lymphatic malformations [ ].

Low-grade fever, nausea and vomiting, and an inflammatory reaction at the injection site were commonly reported, whereas joint pain and mild liver dysfunction were seldom described.