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In controlled studies, oxaprozin caused adverse effects in 23–58% of patients [ ]. It was considered better than aspirin and similar to other NSAIDs in long-term studies [ ]. However, treatment had to be interrupted owing to adverse effects in 8–31% of patients.
Headache, dizziness, vertigo, and tinnitus are less frequent with oxaprozin than with indometacin or aspirin [ , ].
Drug-induced pseudoporphyria has been ascribed to oxaprozin [ ].
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