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Leucocytosis


Leucocytosis is an increase in the absolute count of circulating white blood cells. The normal range is 4–11 × 10 9 /L. It may involve any of the types of white cells, but a polymorphonuclear leucocytosis, i.e. neutrophilia, is the most common.

Causes

Neutrophilia

Physiological

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    Neonates

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    Exercise

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    Pregnancy

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    Childbirth

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    Lactation

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    Stress

Bacterial infection,

e.g. acute appendicitis, pyelonephritis

Acute non-infective inflammation

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    Surgery

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    Burns

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    Infarction, e.g. myocardial infarction, mesenteric infarction

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    Crush injuries

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    Rheumatoid arthritis

Acute haemorrhage and haemolysis

METABOLIC

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    Uraemia

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    Diabetic ketoacidosis

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    Gout

Chronic myeloproliferative disease

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    CML (chronic myeloid leukaemia)

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    Polycythaemia rubrum vera

  • ●

    Myelofibrosis

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