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Klinefelter syndrome


Definition

  • Klinefelter syndrome (or 47,XXY or XXY syndrome) is a condition in which males have an extra X chromosome.

Clinical features

Epidemiology

  • Klinefelter syndrome is the most common sex chromosome disorder in males and the second most common condition caused by the presence of extra chromosomes.

  • Incidence is 1/1000 males.

  • One in every 500 males has an extra X chromosome but does not have the syndrome.

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