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Introduction and classification of inflammatory bowel diseases
Abbreviations
ankylosing spondylitis Crohn’s disease extraintestinal manifestations gastrointestinal inflammatory bowel disease inflammatory bowel disease variant indeterminate colitis pyoderma gangrenosum tumor necrosis factor ulcerative colitis AS
CD
EIM
GI
IBD
IBD-V
IC
PG
TNF
UC
Introduction
Generally speaking, inflammatory bowel disease (IBD) consists of two classic forms: Crohn’s disease (CD) and ulcerative colitis (UC). CD and UC present with distinctive clinicopathological features. The diagnosis of IBD is made based on a combined assessment of clinical, endoscopic, imaging, and histologic features. Classic CD is characterized by the presence of transmural, granulomatous, skip lesions at any part of gastrointestinal (GI) tract, whereas classic UC is featured with diffuse mucosal inflammation starting from the rectum.
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