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Introduction and classification of inflammatory bowel diseases
Abbreviations
AS
ankylosing spondylitis
CD
Crohn’s disease
EIM
extraintestinal manifestations
GI
gastrointestinal
IBD
inflammatory bowel disease
IBD-V
inflammatory bowel disease variant
IC
indeterminate colitis
PG
pyoderma gangrenosum
TNF
tumor necrosis factor
UC
ulcerative colitis
Introduction
Generally speaking, inflammatory bowel disease (IBD) consists of two classic forms: Crohn’s disease (CD) and ulcerative colitis (UC). CD and UC present with distinctive clinicopathological features. The diagnosis of IBD is made based on a combined assessment of clinical, endoscopic, imaging, and histologic features. Classic CD is characterized by the presence of transmural, granulomatous, skip lesions at any part of gastrointestinal (GI) tract, whereas classic UC is featured with diffuse mucosal inflammation starting from the rectum.
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