Inosine pranobex

General information

Inosine pranobex is a synthetic product, also known as isoprinosine or inosine dimepranol acedobene, with antiviral properties that are assumed to be related to its effect on T cell-mediated immunity rather than to direct antiviral activity. It has been tried in a wide range of viral diseases and also in rheumatoid arthritis [ ], multiple sclerosis [ ], and alopecia [ ]. However, clinical trials have mostly shown only modest therapeutic benefit or none at all [ , ], and no specific adverse effects or reactions, except for an increase in serum uric acid concentrations [ ], reflecting the metabolic pathways of purines [ ].