Hydrazine

General information

Hydrazine sulfate has been claimed to be effective in the management of cancers [ , ] and has been promoted as an alternative cancer cure [ ]. However, double-blind, randomized, placebo-controlled studies have suggested no benefit from hydrazine [ ], and it is itself carcinogenic. Hydrazine can arise as a metabolite of drugs such as isoniazid [ ] and atazanavir [ ] and may be involved in isoniazid-induced hepatotoxicity [ ]. Hydrazine-containing fuels are used as propellants for missiles and in jet aircraft, and occupational exposure can cause adverse reactions.

Organs and systems