Diarrhoea is an increased frequency of abnormally loose motions. The diagnosis of diarrhoea must be related to the patient’s normal bowel habit.

Causes

Intestinal

Infective enteritis

Non-specific, bacterial

  • Campylobacter spp • (rare in tropical Africa)

  • Salmonella spp • (rare in tropical Africa)

  • Escherichia coli

  • Clostridium difficile

  • Staphylococci

  • Shigella spp

  • Vibrio cholerae

  • Yersinia enterocolitica (common in the Indian sub-continent)

Viral, fungal, protozoal

  • Cryptosporidium spp

  • Giardia lamblia (more common in children worldwide)

  • Entamoeba histolytica

Inflammatory

  • Ulcerative colitis

  • Crohn’s disease ( Fig. 13 )

    Figure 13, Small bowel enema showing Crohn’s disease .

Malabsorption

  • Coeliac disease

  • Blind loop syndrome

  • Short bowel syndrome

  • Radiation

Neoplastic

  • Carcinoma

  • Villous adenoma

Other intestinal

  • Diverticular disease • (rare in rural Africa and Asia)

  • Irritable bowel syndrome

  • Faecal impaction – overflow diarrhoea

  • Ischaemic colitis

  • Ileocolic fistula

Gastric

  • Post-vagotomy (vagotomy rarely performed nowadays)

Pancreatic

  • Chronic pancreatitis

  • Cystic fibrosis

  • Carcinoma

  • Pancreatic resection

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