General information

Dialysis fluids are solutions of electrolytes formulated in concentrations similar to those of extracellular fluid or plasma. They contain, or may contain:

  • sodium;

  • chloride;

  • bicarbonate or lactate;

  • calcium;

  • magnesium;

  • potassium;

  • glucose;

  • amino acids;

  • icodextrin.

Dialysis fluids are provided in a sterile concentrated form for dilution with water before use; the water used need not be sterile.

Icodextrin

Icodextrin (rINN) is a maltodextrin glucose polymer with a mean molecular weight of 20 kDa, which is broken down to maltose. It is used as an alternative to glucose as the active osmotic agent for peritoneal dialysis. Icodextrin is similar in structure to dextran, but has improved ultrafiltration properties, because it is less well absorbed than glucose.

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