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Dexibuprofen is the dextrorotatory isomer of ibuprofen. Clinical experience is still inadequate to judge its safety profile, although there are claims that it is of comparable safety to celecoxib [ ].
The pharmacokinetics of dexibuprofen 400 mg and ibuprofen arginate 600 mg have been compared in 24 healthy volunteers in an open, randomized, two-period, crossover study [ ]. Ibuprofen arginate had a 45% higher C max and its t max occurred 2 hours earlier, suggesting faster absorption.
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