Corticosteroids—glucocorticoids, intranasal

General information

The safety of nasal glucocorticoids in the treatment of allergic rhinitis has been reviewed [ , ]. The local application of glucocorticoids for seasonal or perennial rhinitis often results in systemic adverse effects. The use of nasal sprays containing a glucocorticoid that has specific topical activity (such as beclomethasone dipropionate or flunisolide) seems to reduce the systemic adverse effects, but they can nevertheless occur, even to the extent of suppression of basal adrenal function in children [ ]. Local adverse effects include Candida infection, nasal stinging, epistaxis, throat irritation [ ], and, exceptionally, anosmia [ ].

Organs and systems