Chronic nonobstructive pyelonephritis


  • Pathological changes observed in the kidney as the result of vesicoureteral reflux (VUR), intrarenal reflux, and repeated UTIs; also termed reflux nephropathy

Clinical features


  • VUR occurs in approximately 1% of children and is found in 30%–50% of children investigated for UTIs.

  • Siblings of children affected with VUR are at higher risk.

  • Of the patients receiving dialysis, 11%–20% have a diagnosis of chronic pyelonephritis not otherwise specified.

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