KEY POINTS A key physiologic attribute that defines the quality of a MPI agent is defined by the relationship between the tracer uptake and MBF. A linear relationship maximizes the sensitivity of the tracer to identify flow-limiting coronary artery stenosis.…
KEY POINTS Accurate quantitative MBF quantification requires an understanding of the technical capabilities of the instrumentation and quantitative software used to make the measurements. Quality control of MBF studies includes careful assessments of the timing and quality of the injected…
KEY POINTS The radionuclides of interest for PET emit positrons, the antiparticles of electrons. Positrons interact with free electrons to produce two back-to-back 511-keV annihilation photons; PET imaging is based on coincidence detection of these photons, not of positrons. Commercial…
KEY POINTS Conventional gamma cameras use one to three detectors, based on a NaI scintillation crystal and a photomultiplier tube array, that rotate around the patient. Cameras commonly use parallel-hole collimators for which sensitivity is constant, but spatial resolution degrades…
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Fourier transforms (FTs) play an important role in tomographic reconstruction (see Chapter 16 ) and in computer implementation of convolutions (see Appendix G ). As well, they are the basis for the modulation transfer function (MTF), one of the methods…
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