KEY POINTS Cardiac amyloidosis is often underdiagnosed, misdiagnosed, or diagnosed late in the natural course of the disease. Accurate diagnosis and typing of cardiac amyloidosis are both critical for initiation of appropriate therapy. Novel therapies appear to be more effective…
KEY POINTS Clinical manifestations of CS include heart block, ventricular arrythmias, SCD, and HF. Among patients with biopsy-proven or a clinical diagnosis of extracardiac sarcoidosis, any signs or symptoms of cardiac involvement should prompt evaluation with advanced imaging with CMR…
KEY POINTS CAV remains a major limitation for the long-term success of cardiac allografts. The high prevalence of renal dysfunction has limited the use of invasive coronary angiography. The evaluation of asymptomatic and symptomatic individuals with suspected or known CAV…
KEY POINTS Current conventional methods to assess arrhythmic risk, including their guidance for implantation of a cardioverter defibrillator, have recognized shortcomings. Radionuclide imaging can enhance other methods to assess arrhythmic risk through its ability to better assess the underlying pathophysiologic…
KEY POINTS In HF patients, CAD may be causal, contributory, or coincidental. The determination of the role of CAD in the patient’s cardiomyopathy is essential to determine the potential additive role of revascularization or device therapy over optimal medical therapy.…
KEY POINTS Myocardial metabolism is inherently and intimately related to cardiac function. The heart is a metabolic omnivore that uses multiple different substrates for the generation of energy to sustain function. Nuclear cardiology techniques including SPECT, and especially PET, can…
KEY POINTS Noninvasive imaging plays an important role in the evaluation of patients with new-onset HF. Documentation of angiographic CAD is often a first-line test and is supported by guidelines. The presence of angiographic CAD does not establish a causal…
KEY POINTS Radionuclide MPI using SPECT or PET techniques is a widely used approach to identify the presence of CAD-related perfusion abnormalities and assess LV function. There exists an extensive literature supporting the use of these techniques in prognostication, and…
KEY POINTS Heart disease remains the number one cause of death in women worldwide. Compared with men, women with symptoms consistent with IHD often present without obstructive CAD on coronary angiography and have a higher prevalence of persistent angina, nonobstructive…
KEY POINTS CVD is highly prevalent in patients with CKD. Both conditions seem to worsen each other’s prognosis and complicate most interventions. The most common cause of death in patients with CKD or on dialysis is CVD. Patients with CKD…