Category Pathology

Invasive urothelial carcinoma

Definition Carcinoma derived from the urothelial lining of the urinary tract that invades into the underlying tissues Clinical features Epidemiology Urothelial carcinoma occurs most often in the urinary bladder with lower incidence in the kidneys, ureters, and urethra. Urothelial carcinoma…

High-grade papillary urothelial carcinoma

Definition Papillary urothelial neoplasm shows significant architectural and cytologic atypia that are apparent at low magnification Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Low-grade papillary urothelial carcinoma

Definition Papillary neoplasm lined by urothelium with easily recognizable variation in cytologic features and characterized by an overall orderly appearance of the urothelium lining papillary fronds Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access…

Inverted papilloma

Definition Benign urothelial neoplasm with a predominant endophytic pattern of growth Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Urothelial papilloma

Definition Benign exophytic urothelial neoplasm characterized by simple, usually nonbranching papillary fronds lined by normal-appearing urothelium Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Urothelial carcinoma in situ

Definition Flat urothelial lesion of the surface urothelium that is composed of cytologically malignant high-grade cells. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Urothelial dysplasia

Definition Presence of distinct cytological and architectural atypia in flat urothelium falling short of the diagnosis of urothelial carcinoma in situ (CIS) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Urothelial atypia of unknown significance

Definition A descriptive category rarely used to describe flat urothelial lesions in which the pathologist is uncertain whether changes are reactive or neoplastic Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Reactive urothelial atypia

Definition Morphological changes in urothelial cells, predominantly nuclear, seen in response to a stimulus Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…