Invasive urothelial carcinoma


  • Carcinoma derived from the urothelial lining of the urinary tract that invades into the underlying tissues

Clinical features


  • Urothelial carcinoma occurs most often in the urinary bladder with lower incidence in the kidneys, ureters, and urethra.

  • Urothelial carcinoma is the most common type of bladder cancer in the United States.

  • Males are affected three- to fourfold more frequently than are females.

  • Smoking and occupational exposure to aromatic amines are the most significant risk factors.

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