Category Pathology

Adenocarcinoma

Definition Malignant neoplasm showing pure glandular phenotype Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Villous adenoma

Definition Benign glandular neoplasm of the bladder, typically with a papillary–villiform growth pattern, that is histologically indistinguishable from similar neoplasms of the colorectum Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Urothelial carcinoma with sarcomatoid differentiation

Definition Biphasic malignant neoplasms with morphologic or immunohistochemical evidence of epithelial and mesenchymal differentiation; a common clonal origin for the carcinomatous and sarcomatous components is presumed. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access…

Urothelial carcinoma with unusual stromal reactions

Definition Four types. In the primary or metastatic sites, urothelial carcinoma with stroma that: Has pseudosarcomatous response; Shows osseous or cartilaginous metaplasia; Contains osteoclast-type giant cells; or Has prominent lymphoid infiltrate Clinical features Epidemiology Rare urothelial carcinoma variant Presentation Hematuria…

Small cell carcinoma of the urinary bladder

Definition High-grade carcinoma with neuroendocrine differentiation, morphologically identical to its pulmonary counterpart Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Undifferentiated urothelial carcinomas

Definition This category contains very poorly differentiated tumors with mixed morphologies (such as small cell undifferentiated carcinoma), giant cell carcinoma, and large cell undifferentiated carcinoma. Clinical features Epidemiology Rare tumors with limited available information Occurs most commonly in older males…

Urothelial carcinoma with rhabdoid differentiation

Definition Unusual variant of urothelial carcinoma characterized by presence of cells with prominent rhabdoid features Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

Urothelial carcinoma with syncytiotrophoblastic giant cells

Definition Unusual form of divergent differentiation in urothelial carcinoma characterized by the presence of human chorionic gonadotrophin (hCG) positive syncytiotrophoblastic giant cells or by a choriocarcinoma component Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full…

Urothelial carcinoma, giant cell variant

Definition Urothelial carcinoma entirely or partially composed of pleomorphic giant cells Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here