Introduction This chapter discusses the use and techniques of pediatric electromyography (EMG). In a comprehensive text on neuromuscular disease such as this, targeted towards clinicians in neuromuscular medicine, the intention of this chapter is not to make readers experts in…
Introduction Many neuromuscular disorders in children are single gene disorders, and therefore genetics plays a primary role in the diagnosis of many neuromuscular conditions. Establishing a definitive molecular genetic diagnosis provides clarity about prognosis; suggests possible therapeutic strategies; allows patients,…
Acknowledgments The authors thank Erika Woodrum and the FES Center for their assistance in preparing illustrations. This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs through the Peer Reviewed Medical Research Program under…
The field of pediatric neuromuscular disorders has continued to expand scientifically since the era of molecular neurogenetics began in the mid-1980s. The rapid changes in the field may be overwhelming to busy, practicing clinicians on a day-to-da… Introduction The role…
Introduction Neurological and neuroanatomical injuries and disorders affect a large number of people worldwide, and often result in movement impairment and inability to perform everyday tasks, such as communicating, reaching, and grasping, independently. Persons who have experienced neurological injuries, such…
Acknowledgments This work was supported by the NIH (EB00856, EB006356, and EB018783), the US Army Research Office (W911NF-08-1-0216, W911NF-12-1-0109, W911NF-14-1-0440), and Fondazione Neurone. Introduction Overview of This Chapter Brain–computer interfaces (BCIs) measure brain activity, extract features from that activity, and…
Acknowledgments I would like to thank the many students and colleagues who are or have been part of the Brown University team that has laid the groundwork and implemented the translation of brain–computer interfaces, as well as the larger Braingate…
Introduction Magnetic resonance imaging (MRI) has been utilized in the clinical setting for more than three decades. During this time, the technology has continued to evolve to improve image quality, acquisition time, and patient comfort. These changes have yielded MRI…
Overview Neural stimulation is an established therapy for the treatment of chronic pain ( ), movement disorders ( ), epilepsy ( ), and urinary and bowel control ( ), and is now being investigated for numerous other psychological and neurological…
Background The International Neuromodulation Society defines therapeutic neuromodulation as “the alteration of nerve activity through the delivery of electrical stimulation or chemical agents to targeted sites of the body” ( ). Neuromodulation is often used to replace surgery with implanted…