Category Anesthesia

Mucopolysaccharidoses

Risk All forms of MPS are autosomal recessive except MPS II (also known as Hunter syndrome), which is X-linked recessive (only males affected). Estimated incidence in USA: 1:30,000. Perioperative Risks MPS pts are at increased anesthetic risk (most complications are…

Moyamoya

Risk Occurs in both children and adults, peak age at 5 y and 40 y, respectively Female-to-male ratio of 1.8:1 Highest incidence in Japanese and Asian populations; familial occurrence 10% Perioperative Risks Stroke Worry About Hypocarbia and hypercarbia Adequate cerebral…

Morbid Obesity

Risk Incidence in USA: Approximately 5% morbidly obese Perioperative Risks Increased morbidity and mortality versus normal BMI from resp and cardiac issues Worry About Challenging procedures: IV start, intubation, ventilation, epidural cath placement. Restrictive pattern of resp disease, hypoxemia, larger…

Mitral Stenosis

Risk Bimodal age distribution: 20–39 y and 50–60 y. Mitral stenosis is 2–3 times more common in women and is the most common valve disease affecting pregnant women. Most common among immigrants to USA from regions where rheumatic fever is…

Mitral Regurgitation

Risk Mitral regurgitation affects more than 2 million people in USA. Incidence of moderate/severe mitral regurgitation: Nearly 20% for age >55 y. Mitral valve prolapse is the primary form of myxomatous degeneration of the valve. Mitral valve prolapse is the…

Mitochondrial Myopathy

Risk More common than previously thought. Prevalence ranges from 1:7000–15,000. Occurrence is usually sporadic or maternally inherited. Perioperative Risks Metabolic acidosis Respiratory and cardiac insufficiency/failure Delayed emergence Worry About Respiratory failure following sedation. Consider aspiration risk. Metabolic acidosis. Hypotension during…

Mitochondrial Disorders

Risk Incidence 4–7:100,000; might be under-reported Perioperative Risks CNS: Facial and bulbar weakness, mental retardation, seizures, learning disabilities, deafness, visual impairment, and stroke-like episodes CVS: Cardiomyopathy and cardiac conduction defects Respiratory: Weakness of muscles of respiration and respiratory failure Other:…