Uses Cocaine (benzoylmethylecgonine) is a commonly abused stimulant drug isolated from leaves of the coca plant ( Erythroxylon coca ). Administered IV, to mucosa, “snorted,” or smoked (“crack”); lipophilic and crosses BBB. Extremely addictive; 5 million Americans are regular users…
Uses Phosphodiesterase inhibitor with antiplatelet aggregation and arteriolar vasodilator properties. Prescribed for intermittent claudication in pts with peripheral arterial disease. Lowers restenosis rates after peripheral endovascular procedures in Asian populations. Secondary prevention of cerebral infarction with less hemorrhagic conversion than…
Risk Cancer is the second most common cause of death in USA. In 2016, about 1,685,210 pts will be diagnosed with cancer and 595,690 will die of it. More than two-thirds of all cancers are diagnosed in people 50 y…
Uses Synthesized in 1953, introduced for trigeminal pain in 1962 and for epilepsy in 1965; approved by the USA FDA since 1976 for the following: Epilepsy: Generalized tonic-clonic seizures, partial seizures with complex pathology (psychomotor, temporal), partial seizures with or…
Uses Topical analgesic treatment for diabetic polyneuropathy, postherpetic neuralgia, and other peripheral neuropathic pain; also for osteoarthritis, rheumatoid arthritis, and other painful disorders Spray used as nonlethal force by law enforcement Perioperative Risks None reported. After exposure to aerosolized capsaicin…
Uses Prescribed to treat Htn, angina, supraventricular arrhythmias, cerebral vasospasm, and HCM. Perioperative Risks CCBs are used chronically in a significant proportion of the surgical population. CCBs are utilized in the treatment of Htn, CAD, or supraventricular arrhythmias and syndromes…
Uses Management of opioid addiction Management of chronic pain (“off-label” use for SL buprenorphine and buprenorphine TD patch) Perioperative Risks Challenges in pain management throughout periop period Respiratory depression Can cause neonatal abstinence syndrome You’re Reading a Preview Become a…
Uses Treatment of squamous cell carcinoma Treatment of melanomas and sarcomas Treatment of testicular carcinoma Treatment of Hodgkin and non-Hodgkin lymphoma Sclerosing agent for malignant pleural effusion Perioperative Risks Adverse effects >10%. Acute febrile reactions (25 -50%). Dermatologic: Skin thickening,…
Uses Oral bisphosphonates: Alendronate (Fosamax), risedronate (Actonel): Prevention and treatment of postmenopausal osteoporosis, prevention and treatment of glucocorticoid-induced osteoporosis, treatment of osteoporosis in men, and Paget disease of bone Etidronate (Didronel): Prevention and treatment of postmenopausal osteoporosis and Paget disease…
Uses Available PO and IV. Prescribed long term for stable angina, systolic CHF, MI (secondary prevention), Htn, and AFIB (for control of heart rate). No longer considered first-line Rx for essential Htn, especially in elderly pts. Long-term Rx must be…