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When it comes to direct, integrated, daily management of cardiac and pulmonary physiology, no specialty compares with anesthesiology. A sound understanding of the separate and integrated fundamentals of cardiorespiratory physiology is essential for an anesthesia provider to rapidly manage both…

The basic principles of pharmacology are a fundamental element of an anesthesia provider's knowledge base. This chapter provides an overview of key principles in clinical pharmacology used to describe anesthetic drug behavior. Box 4.1 lists definitions of some basic pharmacologic…

Clinician well-being has emerged as a critical issue because of widespread clinician burnout. There is growing recognition that a combination of individual strategies and systems-level solutions is required to successfully promote clinician well-being. Interventions to prevent burnout are more effective…

The challenges of learning perioperative anesthesia care have grown considerably as the specialty has evolved. The beginning anesthesia trainee is faced with an ever-increasing quantity of literature and the need for increased knowledge and adequate patient care experiences. Healthcare systems…

. Surgery preceded the development of anesthesia as a medical specialty, with significant implications. Surgery has been performed for thousands of years. Archaeologists have discovered human skulls from prehistoric times with evidence of trephination, a surgical procedure involving drilling or…

Key Points ▪ The medical literature can be accessed in many ways, ranging from the primary literature as indexed in sources like PubMed, to sources catering to medical professionals, and via the lay press and social media as well. ▪…

Key Points ▪ Clinical research describes the characteristics and mechanisms of disease and injury in humans and investigates drugs, devices, diagnostic products, and bundles of care with the aim of providing high-quality evidence to guide clinical practice that improves patients’…

Key Points ▪ Exposure to waste anesthetic gas in clinical practice is unavoidable. In the United States, the limits of exposure to waste gases are set by the National Institute for Occupational Safety and Health (NIOSH), which recommends a time-weighted…

Key Points ▪ Major burn injury results in pathophysiologic changes affecting virtually all organs from the onset of injury until wounds are healed. Anesthesiologists are often called on to care for burn injury patients through their hospitalization including acute airway…

Key Points ▪ Cardiac arrest is a major public health issue worldwide. Despite significant advances in resuscitation science, survival rates remain considerably low. Improvement of patient survival and neurologic outcome relies on the development and implementation of vigorous and evidence-based…