General information Etacrynic acid (ethacrynic acid) is a loop diuretic with similar actions to furosemide and bumetanide. However, it causes more adverse reactions than other loop diuretics and offers no clear advantages. Organs and systems Sensory systems Etacrynic acid is…
General information For a complete account of the adverse effects of estrogens, consult the following monographs as well as this one: Diethylstilbestrol Hormonal contraceptives—emergency contraception Hormonal contraceptives—oral Hormone replacement therapy—estrogens Hormone replacement therapy—estrogens + androgens Hormone replacement therapy—estrogens + progestogens.…
See also Omeprazole ; Proton pump inhibitors General information Esomeprazole is the S-isomer of omeprazole. The pharmacology, pharmacokinetics, efficacy, and safety of esomeprazole have been reviewed [ ]. Esomeprazole produces acid control comparable to that of currently available proton pump…
See also Beta-adrenoceptor antagonists General information Esmolol is a β 1 -selective adrenoceptor antagonist with an extremely short half-life (about 10 minutes), because of extensive metabolism by esterases in blood, liver, and other tissues. Organs and systems You’re Reading a…
General information Erythropoietin is an endogenous glycosylated protein hormone that is produced mainly in the kidneys and stimulates the production of members of the erythroid series of blood cells. Epoetin is the name that has been given to recombinant forms,…
See also Macrolide antibiotics General information For some decades erythromycin was the only macrolide antibiotic available, but with the development of new macrolides with remarkable pharmacokinetic and safety features [ ], it has met fierce competition and has, at least…
General information Tyrosine kinase inhibitors are effective in the targeted treatment of various malignancies. Imatinib was the first to be introduced into clinical oncology, and it was followed by drugs such as erlotinib, gefitinib, sorafenib, sunitinib, and dasatinib. Although they…
General information The genera in the family of Ericaceae ( Table 1 ) include heather, huckleberry, and rhododendron. Table 1 Genera of Ericaceae Agarista (Florida hobblebush) Epigaea (trailing arbutus) Menziesia (menziesia) Andromeda (bog rosemary) Erica (heath) Ornithostaphylos (ornithostaphylos) Arbutus (madrone)…
General information The ergot alkaloids are dopamine receptor agonists. Ergot derivatives include ergotamine tartrate, dihydroergotamine, ergometrine (also called ergonovine), and methylergotamine (also called methylergonovine). They are potent α 1 -adrenoceptor and 5-HT receptor antagonists. Ergotamine and dihydroergotamine Ergotamine and dihydroergotamine…
General information Eptifibatide is a glycoprotein IIb/IIIa inhibitor. Drug studies Comparative studies In a systematic review of comparisons of eptifibatide (n = 2812) and abciximab (n = 729), there were no differences in the incidences of in-hospital death (4.1% with…