See also Anorectic drugs General information Despite the withdrawal of the fenfluramines, the appetite suppressants phendimetrazine and phentermine have remained in widespread use for the treatment of obesity. With phentermine, adverse reactions due to stimulation of the central nervous system…
General information Phenoxybenzamine is a non-selective irreversible alpha-adrenoceptor antagonist. It is given orally in total daily doses up to 60 mg for management of pheochromocytoma, and lower doses have been used to relieve bladder obstruction before surgery. The maximum effect…
See also Opioid receptor agonists General information Phenoperidine is a potent opioid analgesic often used in neuroleptanalgesia and as a respiratory depressant in ventilated patients. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…
See also Physical contraceptives—spermicides General information Phenol is a benzyl alcohol and a major oxidized metabolite of benzene that was introduced into medicine as an antiseptic [ ]. Although it can be prepared in an aqueous solution or in glycerine,…
See also Antiepileptic drugs ; Barbiturates ; Primidone General information Because it is cheap and of unquestioned efficacy, phenobarbital is still widely prescribed around the world, for both epilepsy [ ], including status epilepticus [ , ], and as an…
See also Anorectic drugs General information Phenmetrazine and phendimetrazine are central stimulants and indirect sympathomimetics related to dexamfetamine. Phendimetrazine is about 30% rapidly metabolized to phenmetrazine [ ]. Reported adverse reactions include glossitis, stomatitis, dry mouth, nausea, abdominal pain, cramps,…
See also Antihistamines General information Pheniramine is a first-generation antihistamine. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Antihistamines General information Phenindamine is an antihistamine that is reputed to cause stimulation rather than sedation in some patients. However, in one small study the central nervous system effects of phenindamine were intermediate between those of terfenadine and…
See also Monoamine oxidase inhibitors General information Phenelzine is a non-selective monoamine oxidase (MAO) inhibitor. Organs and systems Nervous system A potential risk of using a non-selective inhibitor in patients with Parkinson’s disease is illustrated by separate reports of the…
General information Phencyclidine or 1-(1-phenylcyclohexy-1) piperidine (known as PCP, “angel dust”, and many other names) was originally developed as an anesthetic, but was abused as an illicit drug from the late 1960s onwards. It is a dopamine receptor agonist and…