See also Cytotoxic and immunosuppressant drugs General information Anthracyclines form a broad group of antitumor drugs within the group of cytotoxic antibiotics. The lead compounds were doxorubicin and daunorubicin; analogues include epirubicin, idarubicin, and aclarubicin. Mitoxantrone and pixantrone are related…
See also Antihistamines General information Antazoline is a first-generation antihistamine. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information Antacids are alkalis, such as aluminium hydroxide, magnesium salts (magnesium hydroxide and magnesium trisilicate), sodium bicarbonate, and calcium hydroxide. They are generally formulated in combinations (for example magnesium hydroxide + aluminium hydroxide, known as co-magaldrox), often with other…
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General information Drug substances of animal origin can produce IgE-mediated or non-IgE-mediated anaphylactic reactions, particularly after parenteral administration [ ]. Animal products can also transmit an infectious disease because of the presence of a pathogenic microbe. The following products are…
See also Echinocandins General information Anidulafungin, an echinocandin, is an antifungal drug that acts by inhibiting β(1,3)- d -glucan synthase, which regulates the formation of β(1,3)- d -glucan, a major component of fungal cell walls [ ]. Its main adverse…
General information Angiotensin-converting enzyme (ACE) inhibitors inhibit the conversion of angiotensin I to angiotensin II ( Figure 1 ). The ACE is also a kininase, and so ACE inhibitors inhibit the breakdown of kinins. Some of the adverse effects of…
See also individual agents General information Inhibition of the renin–angiotensin system by ACE inhibitors has proved efficacious in the treatment of hypertension, cardiac failure, myocardial infarction, in secondary prevention after myocardial infarction, and for kidney protection in diabetic and non-diabetic…
See also individual agents General information Local anesthetics typically contain a hydrophilic tertiary amine group linked to a lipophilic ester or amide. The most commonly used local anesthetics are either amides or esters, as shown in Table 1 . The…
General information The inhalational and injectable agents that are covered in separate monographs are listed in Table 1 . Table 1 Inhalational and injectable anesthetics Inhalational Injectable Halogenated Chloroform Desflurane Enflurane Halothane Isoflurane Methoxyflurane Sevoflurane Trichloroethylene Others Anesthetic ether Cyclopropane…