General information Cetrimonium bromide and cetrimide are quaternary ammonium antiseptics, trimethylammonium derivatives, with similar structures. Cetrimonium bromide is hexadecyltrimethylammonium. Cetrimide is a mixture of tetradecyltrimethylammonium (mostly), dodecyltrimethylammonium, and hexadecyltrimethylammonium. They dissociate in aqueous solution, forming a relatively large and complex…
See also Antihistamines General information Cetirizine is a non-sedating metabolite of hydroxyzine [ ]. There is only minor hepatic metabolism of cetirizine [ ], which is excreted unchanged in the urine. It has not been associated with dysrhythmias. Skin reactions…
General information Cesium is a silver-white soft alkaline metallic element (symbol Cs, atomic number 55). It is used industrially in photoelectric cells and as a catalyst for the hydrogenation of some organic compounds. The natural resonance frequency of excited caesium…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also HMG coenzyme-A reductase inhibitors General information Weight for weight, cerivastatin is the most potent statin. Like other statins, the chance of rhabdomyolysis increases when cerivastatin is taken together with certain other drugs [ ]. Although cerivastatin is degraded…
General information The cephalosporins represent a family of beta-lactam antibiotics originally derived from the naturally occurring cephalosporin C. Isolation of the cephalosporin C nucleus, 7-aminocephalosporanic acid, made it possible to introduce new groups into this molecule to obtain the current…
See also Beta-adrenoceptor antagonists General information Celiprolol is a beta 1 -selective antagonist with partial beta 2 -agonist activity. In healthy volunteers it caused “particularly unpleasant” subjective adverse reactions, including headache, sleepiness, and feeling cold and generally unwell [ ].…
See also COX-2 inhibitors (coxibs) General information Celecoxib is a selective COX-2 inhibitor. Organs and systems Cardiovascular The risk of cardiovascular events with celecoxib has been studied in a systematic review and meta-analysis of randomized double-blind trials of at least…
General information The genera in the family of Celastraceae ( Table 1 ) include bittersweet and khat. Table 1 Genera of Celastraceae Canotia (canotia) Gyminda (false box) Pristimera (pristimera) Cassine (cassine) Lophopyxis Salacia Catha (khat) Maytenus (mayten) Schaefferia (schaefferia) Celastrus…
See also Cephalosporins Organs and systems Nervous system Pseudotumor cerebri has been attributed to ceftriaxone [ ]. Metabolism Although possible interference with the metabolism of carnitine by pivaloylmethyl-esterified beta-lactams is a matter of concern [ ], new similar prodrug derivatives…