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Bleomycin
See also Cytotoxic and immunosuppressant drugs
General information
Bleomycin is a cytostatic drug that causes double-strand breaks in DNA. It has been used to treat Hodgkin’s disease and a variety of solid cancers. It is often used in combination with other anticancer drugs, for example in the regimens known as ABVD (doxorubicin + bleomycin + vinblastine + dacarbazine) and BEP (bleomycin + etoposide + cisplatin). It has also been injected intrapleurally in the management of malignant effusions.
Organs and systems
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