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Batanopride is a substituted benzamide with 5-HT 3 receptor antagonist activity. It is claimed to be free of dopaminergic properties. Clinical studies have concentrated on its use in patients suffering severe vomiting as a result of cytostatic therapy, but have run into problems because of poor tolerance at effective doses. The most important dose-limiting adverse effect is severe hypotension [ ], but diarrhea and electrocardiographic changes also occur.
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