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Bacitracin has mostly dermatological uses. It can cause allergic reactions of the delayed type. A shock-like picture after local application has occurred in a hypersensitive individual [ ]. Since bacitracin is nephrotoxic, it should not be given intraperitoneally to patients with renal impairment.
In a randomized study of the effects of a triple antibiotic ointment (polymyxin B + bacitracin + neomycin) and simple gauze-type dressings on scarring of dermabrasion wounds, the ointment was superior to the simple dressing in minimizing scarring; the beneficial effect on pigmentary changes was especially pronounced [ ].
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