See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information The profile of fenbufen is similar to the profiles of other NSAIDs [ ]. The dropout rate due to adverse reactions was 12–22% in different studies. Organs and systems Respiratory Fenbufen can…
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See also Calcium channel blockers General information Felodipine is a dihydropyridine derivative with diuretic properties [ ]. Its diuretic properties are not unique but are shared by other dihydropyridines. Vasodilatory adverse reactions include flushing, headache, and tachycardia [ , ].…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Felbinac, an active metabolite of fenbufen, is used as a gel for topical treatment and has been thought to be equivalent to ibuprofen [ ]. You’re Reading a Preview Become a Clinical…
See also Antiepileptic drugs General information Felbamate is a broad-spectrum antiepileptic drug, whose use has been drastically curtailed owing to the risks of aplastic anemia and hepatotoxicity. Benefit to harm balance The Quality Standards Subcommittee of the American Academy of…
General information Originally claimed, from animal experiments, to be of rapid onset, short duration, and free of important adverse effects and reactions, this non-depolarizing relaxant has been found to be less satisfactory in man. The usual doses are 0.5–0.75 mg/kg,…
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See also Histamine H 2 receptor antagonists General information Famotidine is a histamine H 2 receptor antagonist. It does not affect drug metabolism and it has been claimed to be free of the antiandrogenic effect of cimetidine; however in one…
General information Famciclovir is an oral prodrug of penciclovir, a selective antiviral drug with activity against Varicella zoster virus, Herpes simplex virus types 1 and 2, and Epstein–Barr virus, as well as human hepatitis B virus. After oral administration, famciclovir…
See also individual agents General information The direct inhibitors of factor Xa are short polysaccharides [ ]. They include rivaroxaban [BAY 59-7939; 5-chloro-N-(({(5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide)], apixaban, edoxaban, otamixaban, and DX-9065 [(+)-2S-2-[4-[[(3S)-1-acetimidoyl-3-pyrrolidinyl]oxy]phenyl]-3-(7-amidino-2-naphthyl) propanoic acid hydrochloride pentahydrate]. Direct inhibitors of factor Xa bind to…