Diastology

Diabetes Mellitus

Case Study A 65-year-old male presents with exertional dyspnea for investigation. He states his dyspnea worsens when walking up a hill. For history, he has type 2 diabetes (treated with metformin), hypertension, dyslipidemia, and Barrett’s esophagus. He previously had an…

Coronary Artery Disease

Introduction While coronary artery disease (CAD) and hypertension are common comorbidities in diastolic dysfunction, and heart failure with preserved ejection fraction (HFpEF), relatively less attention has been paid to the interaction between CAD and diastolic dysfunction. This chapter is devoted…

Primary Restrictive, Infiltrative, and Storage Cardiomyopathies

Introduction A classification serves to bridge the gap between ignorance and knowledge. J.F. Goodwin Historically, restrictive cardiomyopathies were among the three primary forms of idiopathic heart muscle diseases, characterized by the World Health Organization as “restrictive filling and reduced diastolic…

Valve Disease

Introduction Mild degrees of valvular heart disease are very prevalent in adult patients with heart failure symptoms. Given that these are often patients with hypertension, aortic valve sclerosis and mitral annular calcification, frequently accompanied by some degree of mitral regurgitation,…

ASE/EACVI Diastolic Guidelines: Strength and Limitations

Case Study A 56-year-old obese woman with exertional dyspnea was referred for evaluation of suspected heart failure with preserved ejection fraction (HFpEF). She had a past medical history of Crohn Crohn’s disease, hypothyroidism, and asthma. She had been medically treated…