Cardio-Oncology Practice Manual: A Companion to Braunwald’s Heart Disease

Long-term complications of chemotherapy

Open full size image KEY POINTS Despite improvement in cancer survival, many cancer survivors have shortened life spans owing to the late effects of cardiovascular disease (CVD) from their cancer and its treatment Cancer therapeutics can lead to a wide…

Cardiovascular testing in patient with cancer

Open full size image KEY POINTS New imaging modalities play a central role in identifying cardiovascular complications. Cardiotoxicity can manifest in a number of ways, depending on the agent, and can include disease states such as heart failure and cardiomyopathy,…

Pulmonary disease during cancer therapy

Open full size image KEY POINTS Pulmonary complications in patients with cancer may involve any intrathoracic structures Differential diagnosis of parenchymal infiltrates in patients with cancer includes infection, inflammation, neoplastic involvement, and other miscellaneous diagnoses (e.g., pulmonary edema). Clinical presentation…

Thromboembolic disease treatment during cancer therapy

Open full size image KEY POINTS Active cancer increases the risk of venous thromboembolism (VTE) by four-fold without chemotherapy and seven-fold with chemotherapy The likelihood of developing VTE is highest during the first 3 months after the cancer diagnosis and…

Vascular disease during cancer therapy

Open full size image KEY POINTS Patients who have cancer are at risk of developing vascular complications during cancer therapy owing to preexisting cardiovascular disease and/or risk factors and the toxicity potential of cancer therapeutics Three principal presentations of arterial…