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Additional content is available online at Elsevier eBooks for Practicing Clinicians Scope of the Problem Diabetes Mellitus Diabetes mellitus (DM) involves insufficient production of insulin and/or failure to respond appropriately to insulin, resulting in hyperglycemia. Table 31.1 summarizes the current…

Additional content is available online at Elsevier eBooks for Practicing Clinicians A medical perspective defines obesity as excess body fat associated with comorbid conditions and increasing mortality risk. This chapter discusses basic concepts on the cause of obesity as it…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Together with physical activity, smoking cessation, sleep, and stress reduction, a healthy diet forms the foundation for prevention and treatment of cardiometabolic diseases, including coronary heart disease (CHD), stroke,…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Wild plants belonging to the Nicotiana genus were first domesticated and cultivated in the Americas. They were used by Amer-Indians for many centuries in religious and healing practices. Early…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Atherosclerotic cardiovascular diseases (ASCVDs) represent a major burden to society and on national health care systems. Despite public health measures aimed at decreasing saturated fat consumption and cigarette smoking…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Primary hypertension is a key contributor to premature morbidity and mortality in the United States and consistently ranks among the top two risk factors worldwide for global disease burden…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Overview Trends in Cardiovascular Disease and Risk Factors Global Trends Cardiovascular disease remains the leading cause of death worldwide, accounting for approximately 18 million deaths in 2017, with most…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Overview and Background The 20th century witnessed a remarkable evolution in concepts concerning the pathogenesis of atherosclerosis. This disease has a venerable history, having left traces in the arteries…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Cardiovascular morbidity and mortality represent a special concern in patients with known (or with risk factors for) cardiovascular disease who undergo noncardiac surgery. The cost of perioperative myocardial injury…

Acknowledgment This section extends the corresponding chapter of prior editions of Braunwald’s Heart Disease , which was authored by Drs. Charles J. Davidson and Robert O. Bonow. Additional content is available online at Elsevier eBooks for Practicing Clinicians Introduction to…