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Apixaban
See also Factor Xa inhibitors, direct
General information
Apixaban is a follow-up compound with high oral systemic availability (50–85%) and a half-life of about 12 hours. Apixaban is cleared through renal (25%) and fecal routes and is given twice daily. It has been tested in the prevention and treatment of venous thromboembolism, for the prevention of stroke or systemic embolism in patients with atrial fibrillation, and for the management of acute coronary syndrome [ ].
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