Acute kidney injury (acute tubular necrosis)


Definition

  • A clinicopathological entity with pathological changes in the renal tubules when ischemic or toxic injuries affect the kidney

Clinical features

Epidemiology

  • Acute kidney injury (AKI) is the most common cause of acute renal failure.

  • The precipitating events include ischemic episodes and endogenous or exogenous nephrotoxins.

  • Ischemia-induced AKI represents approximately 60% of the cases.

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