Phenmetrazine and phendimetrazine


See also Anorectic drugs

General information

Phenmetrazine and phendimetrazine are central stimulants and indirect sympathomimetics related to dexamfetamine. Phendimetrazine is about 30% rapidly metabolized to phenmetrazine [ ]. Reported adverse reactions include glossitis, stomatitis, dry mouth, nausea, abdominal pain, cramps, constipation, difficulty in micturition, and headache. Because of adverse reactions and the risk of abuse it has been withdrawn in several countries.

Organs and systems

Cardiovascular

A dilated cardiomyopathy has been associated with chronic consumption of phendimetrazine [ ].

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