Benzydamine

General information

Benzydamine is 1-benzyl-3-(3-dimethylaminopropoxy)- H -indazole, used for medical purposes as the hydrochloride. It has analgesic, anti-inflammatory, antipyretic, and local anesthetic effects. In the past it has been especially used in the symptomatic treatment of edematous postoperative or traumatic swelling, non-specific inflammation of the upper respiratory tract, and inflammation of connective tissues and joints.

Benzydamine is marketed in different countries as Difflam or Tantum verde. It is used for the treatment of oral and pharyngeal inflammation from any cause, for example radiotherapy-induced mucositis, stomatitis, Vincent’s angina, necrotic oropharyngeal neoplasms, after surgical operations on the mouth and pharynx, after intubation, and after endoscopic laryngeal surgery. It can be administered as a spray, a gargle solution, a rinsing solution, or lozenges.