External agents and artifacts


Electrocautery

  • Keratinocytes show marked parallel vertical elongation

  • Homogenization of the collagen

Fig. Ap3.1, Electrocautery artifact

Gelfoam

  • Blue-purple, arabesque, netlike pattern with surrounding granulomatous reaction

Fig. Ap3.2, (A,B) Gelfoam

Aluminum chloride

  • Epidermal effacement and horizontal fibrosis consistent with scar and underlying light gray-blue granules, often in histiocytes, with focal calcification

Fig. Ap3.3, (A,B) Aluminum chloride at base of biopsy site

Monsel's solution (ferric subsulfate)

  • Epidermal effacement and horizontal fibrosis with collagen necrosis and chunky golden, refractile pigment in macrophages

  • Perls' iron stain is strongly positive, distinguishing the pigment from melanin

Fig. Ap3.4, Monsel's solution tattoo

You're Reading a Preview

Become a Clinical Tree membership for Full access and enjoy Unlimited articles

Become membership

If you are a member. Log in here