Wegener Granulomatosis (Granulomatosis With Polyangiitis)

Prevalence of 3:100,000 persons affected

More common in the white race; however, no gender affinity

Respiratory failure

Upper airway compromise

Cardiovascular instability

Acute renal failure

Peripheral neuropathy

Bleeding disorder

Medication toxicity, side effects, and interactions

Systemic involvement, primarily respiratory, cardiovascular, and renal systems

Airway compromise

Systemic vasculitis of small, medium, and occasionally large arteries

Characterized by necrotizing granulomatosis of upper and lower respiratory tracts in addition to glomerulonephritis